EVERY ONE MATTERS

You want to put your hepatitis C (Hep C) behind you. And you’ve tried. But sometimes it takes a little more help.

VOSEVI is a Hep C treatment specifically for adults who have been previously treated with an advanced Hep C regimen,* but haven’t been cured. Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed.

VOSEVI is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated) who have previously been treated with a Hep C regimen containing an NS5A inhibitor.

SCROLL TO SEE WHY YOUR CURE MATTERS

*A Hep C regimen containing an NS5A inhibitor, including EPCLUSA®, HARVONI®, Viekira Pak®, Viekira XR®, Technivie®, Zepatier®, and regimens containing Daklinza®.

VOSEVI is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated) who have previously been treated with a Hep C regimen containing an NS5A inhibitor.

Important Safety Information

What is the most important information I should know about VOSEVI?

VOSEVI can cause serious side effects, including:

  • Hepatitis B virus reactivation: Before starting VOSEVI treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with VOSEVI. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking VOSEVI.

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PROVEN TO CURE HEP C PATIENTS LIKE YOU

In a clinical study, VOSEVI had a 96% overall cure rate in adult patients who had Hep C genotype 1, 2, 3, 4, 5, or 6, without cirrhosis or with compensated cirrhosis,* who had been previously treated with certain advanced Hep C regimens.

*Compensated cirrhosis is a type of advanced liver disease in which healthy liver tissue is replaced with scar tissue, but the liver is still able to carry out its important functions.

In a study of 263 patients with genotype 1, 2, 3, 4, 5, or 6 Hep C, without cirrhosis or with compensated cirrhosis, who previously failed a Hep C regimen containing an NS5A inhibitor, 97% (146 out of 150) of patients with genotype 1, 100% (5 out of 5) of patients with genotype 2, 95% (74 out of 78) of patients with genotype 3, 91% (20 out of 22) of patients with genotype 4, 100% (1 out of 1) of patients with genotype 5, and 100% (6 out of 6) of patients with genotype 6 who received VOSEVI once daily for 12 weeks were cured. Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed.

SEE VOSEVI CLINICAL STUDY RESULTS

Important Safety Information

Who should not take VOSEVI?

  • Do not take VOSEVI if you take medicines that contain rifampin (Rifater®, Rifamate®, Rimactane®, Rifadin®).

What should I tell my healthcare provider before taking VOSEVI?

  • Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection or liver problems other than hepatitis C infection; if you have severe kidney problems or are on dialysis; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if VOSEVI will harm your unborn baby or pass into your breast milk.
  • Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. VOSEVI and certain other medicines may affect each other, or may cause side effects.

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SIMPLE TREATMENT REGIMEN

VOSEVI tablet
Not actual size

VOSEVI contains sofosbuvir, the medicine that has helped transform Hep C treatment, combined with 2 additional medicines—creating a highly effective Hep C treatment. With VOSEVI, treatment is one pill, once a day, taken with food for 12 weeks.

LEARN ABOUT VOSEVI COMMON SIDE EFFECTS

Important Safety Information

What are the possible side effects of VOSEVI?

Serious side effects may also include:

  • Slow heart rate (bradycardia): VOSEVI, when taken in combination with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems, may cause slow heart rate. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Get medical help right away if you take amiodarone with VOSEVI and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.

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YOU HAVEN’T BEEN LEFT BEHIND

VOSEVI is a Hep C treatment option for patients just like you*—because your cure matters.

I was a little concerned because I’ve been on Hep C treatments before—but now I’m cured!
- Anthony I.,
VOSEVI patient

*VOSEVI is a Hep C treatment for adults who have genotype 1, 2, 3, 4, 5, or 6 Hep C who have been previously treated with certain advanced Hep C regimens, but haven’t been cured.

LEARN HOW TO GET STARTED WITH VOSEVI

*VOSEVI is a Hep C treatment for adults who have genotype 1, 2, 3, 4, 5, or 6 Hep C who have been previously treated with certain advanced Hep C regimens, but haven’t been cured.

Important Safety Information

What are the possible side effects of VOSEVI? (continued)

The most common side effects of VOSEVI include headache, tiredness, diarrhea, and nausea.

Please see Important Facts about VOSEVI including Important Warning.

VOSEVI is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated) who have previously been treated with a Hep C regimen containing an NS5A inhibitor.

Important Safety Information

What is the most important information I should know about VOSEVI?

VOSEVI can cause serious side effects, including:

  • Hepatitis B virus reactivation: Before starting VOSEVI treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with VOSEVI. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking VOSEVI.

Who should not take VOSEVI?

  • Do not take VOSEVI if you take medicines that contain rifampin (Rifater®, Rifamate®, Rimactane®, Rifadin®).

What should I tell my healthcare provider before taking VOSEVI?

  • Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection or liver problems other than hepatitis C infection; if you have severe kidney problems or are on dialysis; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if VOSEVI will harm your unborn baby or pass into your breast milk.
  • Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. VOSEVI and certain other medicines may affect each other, or may cause side effects.

What are the possible side effects of VOSEVI?

Serious side effects may also include:

  • Slow heart rate (bradycardia): VOSEVI, when taken in combination with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems, may cause slow heart rate. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Get medical help right away if you take amiodarone with VOSEVI and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.

The most common side effects of VOSEVI include headache, tiredness, diarrhea, and nausea.

Please see Important Facts about VOSEVI including Important Warning.